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Por favor, use este identificador para citar o enlazar este ítem: https://hdl.handle.net/20.500.12008/50551 Cómo citar
Título: Does Shiga Toxin-Producing Escherichia coli and Listeria monocytogenes Contribute Significantly to the Burden of Antimicrobial Resistance in Uruguay?
Autor: Mota, María Inés
Vázquez, Sylvia
Cornejo, Cecilia
D’Alessandro, Bruno
Braga, Valeria
Caetano, Ana
Betancor, Laura
Varela, Gustavo
Tipo: Artículo
Palabras clave: Antimicrobial resistance, Shiga toxin-producing Escherichia coli (STEC), Listeria monocytogenes, Zoonotic pathogens, Resistance genes
Fecha de publicación: 2020
Resumen: Shiga toxin-producing Escherichia coli (STEC) and Listeria monocytogenes are worldwide recognized zoonotic pathogens. Recent reports have emerged about the circulation of antimicrobial-resistant STEC and L. monocytogenes isolates. To assess the frequency of antimicrobial resistance and related genes in these pathogens, we studied 45 STEC and 50 L. monocytogenes isolates locally recovered from different sources. Antimicrobial susceptibility testing was performed by disk-diffusion method, and the genomic sequences of three selected STEC and from all 50 L. monocytogenes isolates were analyzed for antibiotic resistance genes. Four STEC and three L. monocytogenes isolates were phenotypically resistant to at least one of the antibiotics tested. Resistance genes aph(3′′)-Ib, aph(3′ )-Ia, aph(6)-Id, blaT EM−1B, sul2, mef(A), and tet(A) were found in a human STEC ampicillin-resistant isolate. All L. monocytogenes isolates harbored fosX, lin, mdrL, lde fepA, and norB. Overall resistance in L. monocytogenes and STEC was low or middle. However, the high load of resistance genes found, even in susceptible isolates, suggests that these pathogens could contribute to the burden of antimicrobial resistance.
EN: Front. Vet. Sci. 7, 2020
Financiadores: Agencia Nacional de Investigación e Innovación (ANII)
Citación: MOTA, MI., VÁZQUEZ, S., CORNEJO, C., y otros. Does Shiga Toxin-Producing Escherichia coli and Listeria monocytogenes Contribute Significantly to the Burden of Antimicrobial Resistance in Uruguay?. Front. Vet. Sci [en línea] 2020, 7. DOI: 10.3389/fvets.2020.583930
Cobertura geográfica: URUGUAY
Licencia: Licencia Creative Commons Atribución (CC - By 4.0)
Aparece en las colecciones: Artículos - Instituto de Higiene



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