Por favor, use este identificador para citar o enlazar este ítem:
https://hdl.handle.net/20.500.12008/51892
Cómo citar
Título: | Glandular odontogenic cyst: insights into a rare and challenging lesion. |
Autor: | Schuch, Lauren Frenzel Silveira, Felipe Martins González Umpiérrez, Maria Natalia Beovide Cortegoso, Aurita Verónica Sicco, Estefanía Bologna-Molina, Ronell Pereira-Prado, Vanesa |
Tipo: | Artículo |
Palabras clave: | Odontogenic lesion, Glandular odontogenic cyst, Diagnostic challenge |
Descriptores: | QUISTES ODONTOGÉNICOS, ODONTOGENIC CYSTS |
Fecha de publicación: | 2025 |
Resumen: | The glandular odontogenic cyst (GOC) is a rare developmental odontogenic cyst characterized by an epithelial lining resembling salivary or glandular tissue. Its aggressive behavior and potential for recurrence pose challenges in both diagnosis and management. This review consolidates current knowledge on etiopathogenesis, clinical presentation, histopathological features, and treatment approaches. GOC primarily affects male adults, often presenting asymptomatically, and is most commonly found in the mandible. Radiographically, it appears as a unilocular or multilocular radiolucency, frequently associated with unerupted teeth. Histologically, GOC is istinguished by a multilocular cystic structure lined with epithelial cells, which may include “hobnail,” clear, and mucous cells. While traditionally thought to lack MAML2 gene rearrangements, recent studies have identified MAML2 fusion transcripts in recurrent GOCs, suggesting a link to aggressive behavior. The differential diagnosis
includes both benign and malignant conditions. Treatment options range from conservative management to radical resection, with recurrence being a notable concern. This review highlights the need for accurate diagnosis and long-term follow-up, as no histopathological features reliably predict recurrence. Further research is needed to optimize treatment strategies and deepen understanding of its biological behavior. |
Editorial: | Brazilian Society of Oral Medicine and Oral Pathology (SOBEP). |
EN: | Journal of Oral Diagnosis, 2025, 10:e292. |
Citación: | Schuch, L, Silveira, F, González Umpiérrez, M, [y otros autores]. "Glandular odontogenic cyst: insights into a rare and challenging lesion". Journal of Oral Diagnosis. [en línea] 2025, 10:e292. |
ISSN: | 2525-5711 |
Licencia: | Licencia Creative Commons Atribución (CC - By 4.0) |
Aparece en las colecciones: | Publicaciones académicas y científicas 2020- - Facultad de Odontología |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | ||
---|---|---|---|---|---|
10532725255711292.pdf | 622,96 kB | Adobe PDF | Visualizar/Abrir |
Este ítem está sujeto a una licencia Creative Commons Licencia Creative Commons