Por favor, use este identificador para citar o enlazar este ítem:
https://hdl.handle.net/20.500.12008/41074
Cómo citar
Registro completo de metadatos
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Rodríguez-Casuriaga, Rosana | - |
dc.contributor.author | Geisinger Wschebor, Adriana | - |
dc.date.accessioned | 2023-11-14T12:32:35Z | - |
dc.date.available | 2023-11-14T12:32:35Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Rodríguez-Casuriaga, R y Geisinger Wschebor, A. "Contributions of flow cytometry to the molecular study of spermatogenesis in mammals". International Journal of Molecular Sciences. [en línea] 2021, 22(3): 1151. 27 h. DOI: 10.3390/ijms22031151. | es |
dc.identifier.issn | 1422-0067 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.12008/41074 | - |
dc.description.abstract | Mammalian testes are very heterogeneous organs, with a high number of different cell types. Testicular heterogeneity, together with the lack of reliable in vitro culture systems of spermatogenic cells, have been an obstacle for the characterization of the molecular bases of the unique events that take place along the different spermatogenic stages. In this context, flow cytometry has become an invaluable tool for the analysis of testicular heterogeneity, and for the purification of stage-specific spermatogenic cell populations, both for basic research and for clinical applications. In this review, we highlight the importance of flow cytometry for the advances on the knowledge of the molecular groundwork of spermatogenesis in mammals. Moreover, we provide examples of different approaches to the study of spermatogenesis that have benefited from flow cytometry, including the characterization of mutant phenotypes, transcriptomics, epigenetic and genome-wide chromatin studies, and the attempts to establish cell culture systems for research and/or clinical aims such as infertility treatment. | es |
dc.format.extent | 27 h. | es |
dc.format.mimetype | application/pdf | es |
dc.language.iso | en | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | International Journal of Molecular Sciences, 2021, 22(3): 1151. | es |
dc.rights | Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014) | es |
dc.subject | Spermatogenesis | es |
dc.subject | Flow cytometry | es |
dc.subject | FACS | es |
dc.subject | Male infertility | es |
dc.title | Contributions of flow cytometry to the molecular study of spermatogenesis in mammals | es |
dc.type | Artículo | es |
dc.contributor.filiacion | Rodríguez-Casuriaga Rosana, IIBCE | - |
dc.contributor.filiacion | Geisinger Wschebor Adriana, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Biología. | - |
dc.rights.licence | Licencia Creative Commons Atribución (CC - By 4.0) | es |
dc.identifier.doi | 10.3390/ijms22031151 | - |
Aparece en las colecciones: | Publicaciones académicas y científicas - Facultad de Ciencias |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | ||
---|---|---|---|---|---|
103390ijms22031151.pdf | 40,46 MB | Adobe PDF | Visualizar/Abrir |
Este ítem está sujeto a una licencia Creative Commons Licencia Creative Commons