Por favor, use este identificador para citar o enlazar este ítem:
https://hdl.handle.net/20.500.12008/30811
Cómo citar
Registro completo de metadatos
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Castells Bauer, Matías | - |
dc.contributor.author | López Tort, Luis Fernando | - |
dc.contributor.author | Colina, Rodney | - |
dc.contributor.author | Cristina, Juan | - |
dc.date.accessioned | 2022-02-09T13:13:42Z | - |
dc.date.available | 2022-02-09T13:13:42Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Castells Bauer, M, López-Tort, F, Colina, R [y otros] "Evidence of increasing diversification of emerging Severe Acute Respiratory Syndrome Coronavirus 2 strains". Journal of Medical Virology. [en línea] 2020, 92: 2165–2172. 8 h. DOI: 10.1002/jmv.26018 | es |
dc.identifier.issn | 1096-9071 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.12008/30811 | - |
dc.description.abstract | On 30th January 2020, an outbreak of atypical pneumonia caused by a novelbetacoronavirus, named severe acute respiratory syndrome coronavirus 2(SARS‐CoV‐2), was declared a public health emergency of international concern bythe World Health Organization. For this reason, a detailed evolutionary analysis ofSARS‐CoV‐2 strains currently circulating in different geographic regions of theworld was performed. A compositional analysis as well as a Bayesian coalescentanalysis of complete genome sequences of SARS‐CoV‐2 strains recently isolated inEurope, North America, South America, and Asia was performed. The results ofthese studies revealed a diversification of SARS‐CoV‐2 strains in three differentgenetic clades. Co‐circulation of different clades in different countries, as well asdifferent genetic lineages within different clades were observed. The time of themost recent common ancestor was established to be around 1st November 2019.A mean rate of evolution of 6.57 × 10−4substitutions per site per year was found.A significant migration rate per genetic lineage per year from Europe to SouthAmerica was also observed. The results of these studies revealed an increasingdiversification of SARS‐CoV‐2 strains. High evolutionary rates and fast populationgrowth characterizes the population dynamics of SARS‐CoV‐2 strains. | es |
dc.format.extent | 8 h. | es |
dc.format.mimetype | application/pdf | es |
dc.language.iso | en | es |
dc.publisher | Wiley-Liss | es |
dc.relation.ispartof | Journal of Medical Virology, 2020, 92: 2165–2172 | es |
dc.rights | Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014) | es |
dc.subject | Coalescent | es |
dc.subject | Coronavirus | es |
dc.subject | Evolution | es |
dc.subject | SARS‐CoV‐2 | es |
dc.title | Evidence of increasing diversification of emerging Severe Acute Respiratory Syndrome Coronavirus 2 strains | es |
dc.type | Artículo | es |
dc.contributor.filiacion | Castells Bauer Matías, Universidad de la República (Uruguay). CENUR | - |
dc.contributor.filiacion | López Tort Luis Fernando, Universidad de la República (Uruguay). CENUR | - |
dc.contributor.filiacion | Colina Rodney, Universidad de la República (Uruguay). CENUR | - |
dc.contributor.filiacion | Cristina Juan, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares | - |
dc.rights.licence | Licencia Creative Commons Atribución (CC - By 4.0) | es |
dc.identifier.doi | 10.1002/jmv.26018 | - |
Aparece en las colecciones: | Publicaciones académicas y científicas - Facultad de Ciencias |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | ||
---|---|---|---|---|---|
10.1002jmv.26018.pdf | 1,68 MB | Adobe PDF | Visualizar/Abrir |
Este ítem está sujeto a una licencia Creative Commons Licencia Creative Commons