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dc.contributor.authorCavalcanti de Lima, J.H.-
dc.contributor.authorMatos, P.C.-
dc.contributor.authorGouvê, C.V. D.de-
dc.contributor.authorCarvalho, W.-
dc.contributor.authorCalvo-Guirado, J.L.-
dc.contributor.authorAragoneses, J.M.-
dc.contributor.authorPérez-Díaz, Leticia-
dc.contributor.authorGehrke, S.A.-
dc.date.accessioned2021-07-22T14:41:32Z-
dc.date.available2021-07-22T14:41:32Z-
dc.date.issued2019-
dc.identifier.citationCavalcanti de Lima, J, Matos, P, Gouvê, C, y otros "In Vitro assessment of the functional dynamics of titanium with surface coating of hydroxyapatite nanoparticles". Materials. [en línea] 2019, 12(5): 840. 14 h. DOI: 10.3390/ma12050840en
dc.identifier.issn1996-1944-
dc.identifier.urihttps://hdl.handle.net/20.500.12008/28676-
dc.descriptionThis article belongs to the Special Issue Clinical Implants and the Biocompatibility of Biodegradable Biomaterialsen
dc.description.abstractManipulation of implant surface characteristics constitutes a promising strategy for improving cell growth and tissue response on a variety of materials with different surface topographies. Mesenchymal progenitor cells with a capacity to respond to titanium surface stimuli and differentiate into osteoblasts were used to perform comparative tests between two different implant topographies, including their functional interaction with pre-osteoblasts directly seeded onto the implants. Functional analysis of nanostructured implant surfaces was performed by in vitro assay analysis. The machined surface of titanium implants (mach group) was used as a control and compared with a nanoparticle HA activated surface implant (nano group), developed by the deposition of pure crystalline hydroxyapatite. Cell culture on the nano group surface resulted in higher cell adhesion and cultured osteoblast viability compared with the mach group. Scanning electron microscope (SEM) images revealed a stable interaction, indicated by the presence of focal cell adhesion formation. These results together with positive mineralization assays showed the nano group to be an excellent scaffold for bone-implant integration.en
dc.format.extent14 h.es
dc.format.mimetypeapplication/pdfes
dc.language.isoenes
dc.publisherMDPIes
dc.relation.ispartofMaterials, 2019, 12(5): 840es
dc.rightsLas obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014)es
dc.subjectImplants surfaceen
dc.subjectMesenchymal cellsen
dc.subjectTitanium implantsen
dc.titleIn Vitro assessment of the functional dynamics of titanium with surface coating of hydroxyapatite nanoparticlesen
dc.typeArtículoes
dc.contributor.filiacionCavalcanti de Lima J.H.-
dc.contributor.filiacionMatos P.C.-
dc.contributor.filiacionGouvê C.V. D.de-
dc.contributor.filiacionCarvalho W.-
dc.contributor.filiacionCalvo-Guirado J.L.-
dc.contributor.filiacionAragoneses J.M.-
dc.contributor.filiacionPérez-Díaz Leticia, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Química Biológica.-
dc.contributor.filiacionGehrke S.A.-
dc.rights.licenceLicencia Creative Commons Atribución (CC - By 4.0)es
dc.identifier.doi10.3390/ma12050840-
Aparece en las colecciones: Publicaciones académicas y científicas - Facultad de Ciencias

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