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Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12008/18484 How cite
Title: Differences in E-Cadherin and Syndecan-1 expression in different types of ameloblastomas
Authors: Carreón Burciaga, Ramón Gil
González González, Rogelio
Molina Frechero, Nelly
López Verdín, Sandra
Pereira Prado, Vanesa
Bologna Molina, Ronell
Type: Artículo científico
Descriptors: AMELOBLASTOMA
Issue Date: 2018
Abstract: Ameloblastomas are a group of benign, locally aggressive, recurrent tumors characterized by their slow and infiltrative growth. E-Cadherin and syndecan-1 are cell adhesion molecules related to the behavior of various tumors, including ameloblastomas. Ninety-nine ameloblastoma samples were studied; the expression of E-cadherin and syndecan-1 were evaluated by immunohistochemistry. E-Cadherin and epithelial syndecan-1 were more highly expressed in intraluminal/luminal unicystic ameloblastoma than in mural unicystic ameloblastoma and solid/multicystic ameloblastoma, whereas the stromal expression of syndecan-1 was higher in mural unicystic ameloblastoma and solid/multicystic ameloblastoma. Synchronicity was observed between E-cadherin and epithelial syndecan-1; the expression was correlated with intensity in all cases. There was a strong association between expression and tumor size and recurrence. The evaluation of the expression of E-cadherin and syndecan-1 are important for determining the potential aggressiveness of ameloblastoma variants. Future studies are required to understand how the expression of these markers is related to tumor aggressiveness.
Publisher: Hindawi Publishing Corporation
IN: Analytical Cellular Pathology, vol. 2018
ISSN: 2210-7177
Citation: Carreón-Burciaga, R, González-González, R, Molina-Frechero, N, López-Verdín, S, Pereira-Prado, V y Bologna-Molina, R. "Differences in E-Cadherin and Syndecan-1 expression in different types of ameloblastomas" [en línea] Analytical Cellular Pathology, vol. 2018
Appears in Collections:Artículos - Facultad de Odontología

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