Título:
Differences in E-Cadherin and Syndecan-1 Expression in Different Types of Ameloblastomas
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Autor:
Carreón Burciaga, Ramón Gil
González González, Rogelio
Molina-Frechero, Nelly
López-Verdín, Sandra
Pereira-Prado, Vanesa
Bologna-Molina, Ronell
González González, Rogelio
Molina-Frechero, Nelly
López-Verdín, Sandra
Pereira-Prado, Vanesa
Bologna-Molina, Ronell
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Artículo
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AMELOBLASTOMA
SINDECANO-1
CADHERINAS
SINDECANO-1
CADHERINAS
Año de publicación:
2018
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Resumen:
Ameloblastomas are a group of benign, locally aggressive, recurrent tumors characterized by their slow and infiltrative growth. ECadherin and syndecan-1 are cell adhesion molecules related to the behavior of various tumors, including ameloblastomas. Ninetynine ameloblastoma samples were studied; the expression of E-cadherin and syndecan-1 were evaluated by immunohistochemistry. E-Cadherin and epithelial syndecan-1 were more highly expressed in intraluminal/luminal unicystic ameloblastom a than in mural unicystic ameloblastoma and solid/multicystic ameloblastoma, whereas the stromal expression of syndecan-1 was higher in mural
unicystic ameloblastoma and solid/multicystic ameloblastoma. Synchronicity was observed between E-cadherin and epithelial syndecan-1; the expression was correlated with intensity in all cases. There was a strong association between expression and tumor size and recurrence. The evaluation of the expression of E-cadherin and syndecan-1 are important for determining the potential aggressiveness of ameloblastoma variants. Future studies are required to understand how the expression of these markers is related to tumor aggressiveness.
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Analytical Cellular Pathology Volume 2018,
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Citación:
Carreón Burciaga, R, González González, R, Molina-Frechero, N. y otros "Differences in E-Cadherin and Syndecan-1 Expression in Different Types of Ameloblastomas". Analytical Cellular Pathology Volume 2018. [en línea] 2018 doi.org/10.1155/2018/9392632.
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Licencia Creative Commons Atribución - No Comercial (CC - By-NC 4.0)
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| Ficheros | Descripción | Tamaño | Formato | ||
|---|---|---|---|---|---|
| Differences in E-Cadherin and Syndecan-1 Expression in Different types of ameloblastomas.pdf | — | 12.9 MB | Adobe PDF |