Título:
Next-Generation Whole-Cell Pneumococcal Vaccine
Otros títulos:
Coordinador:
Director:
Compilador:
Autor:
Morais, Victor
Texeira, Esther
Suarez, Norma
Texeira, Esther
Suarez, Norma
Tutor:
Tipo de documento:
Artículo
Editor:
Palabras clave:
Streptococcus pneumoniae
whole-cell vaccine
RM200
virulence factors
whole-cell vaccine
RM200
virulence factors
Descriptores:
Año de publicación:
2019
Contenido:
Resumen:
Streptococcus pneumoniae remains a major public health hazard. Although Pneumococcal Conjugate Vaccines (PCVs) are available and have significantly reduced the rate of invasive pneumococcal diseases, there is still a need for new vaccines with unlimited serotype coverage, long-lasting protection, and lower cost to be developed. One of the most promising candidates is the Whole-Cell Pneumococcal Vaccine (WCV). The new generation of whole-cell vaccines is based on an unencapsulated serotype that allows the expression of many bacterial antigens at a lower cost than a recombinant vaccine. These vaccines have been extensively studied, are currently in human trial phase 1/2, and seem to be the best treatment choice for pneumococcal diseases, especially for developing countries.
Descripción:
metadata.articulos.dc.description.uri:
Editorial:
EN:
Vaccines. 7, 2019
Financiadores:
Programa de Desarrollo de las Ciencias Básicas (PEDEClBA)
Citación:
MORAIS, V., TEXEIRA, E., SUAREZ, N. Next-Generation Whole-Cell Pneumococcal Vaccine. Vaccines [en línea] 2019, 7. DOI: 10.3390/vaccines7040151
Citación:
metadata.articulos.cc.license.name:
ISBN:
e-ISBN:
ISSN:
ISMN:
Otros identificadores:
Cobertura geográfica:
Cobertura temporal:
Departamento académico:
Grupo de investigación:
Licencia:
Licencia Creative Commons Atribución (CC - By 4.0)
Colecciones:
| Ficheros | Descripción | Tamaño | Formato | ||
|---|---|---|---|---|---|
| Next-Generation Whole-Cell Pneumococcal Vaccine.pdf | Artículo original | 465.83 KB | Adobe PDF |