Título:
Relationship between cognitive reserve (education), social cognition and negative symptoms
Otros títulos:
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Director:
Compilador:
Autor:
Lema Spinelli, Sebastián
Rodríguez-Testal, Juan Francisco
Cabana Fajardo, Álvaro J.
Romano Fuzul, Sandra
Gómez Sena, Leonel Francisco
Rodríguez-Testal, Juan Francisco
Cabana Fajardo, Álvaro J.
Romano Fuzul, Sandra
Gómez Sena, Leonel Francisco
Tutor:
Tipo de documento:
Artículo
Editor:
Palabras clave:
Cognitive reserve
Social cognition
Negative symptoms
Schizophrenia
Psychosis
Mediation analysis
Regression analysis
Social cognition
Negative symptoms
Schizophrenia
Psychosis
Mediation analysis
Regression analysis
Descriptores:
Año de publicación:
2025
Contenido:
Resumen:
Background: Negative symptoms (NS) are a core feature of schizophrenia spectrum disorders, yet their rela-
tionship with cognitive reserve (defined by educational attainment) and social cognition remains underexplored.
This study examined whether education predicts NS and whether this relationship is mediated by social cognition, specifically emotional or inferential theory of mind Reading the Mind in the Eyes Test (RMET) vs. the Hinting Test.
Methods: A mediation model and multiple regression analysis were conducted within an ex-post-facto, cross-
sectional design. The sample included 144 participants: 69 diagnosed with schizophrenia spectrum disorders and
75 healthy controls. Women comprised 52.8 % of the sample, with a mean age of 42.67 years (SD = 15.88). The
average years of formal education were 8.37 (SD = 2.77) in the patient group and 8.62 (SD = 3.66) in the control
group.
Results: The mediation model explained 67.57 % of the variance in NS, with age as a covariate. RMET showed a
significant indirect effect (d = 0.22) in predicting NS, while HT did not (d = 0.12). In the patient group, multiple regression analysis explained 69.2 % of the variance, with education emerging as a significant predictor
of NS.
Conclusions: Education, as an indicator of cognitive reserve, significantly predicts NS. This relationship is
mediated by social cognition, with differential effects depending on the specific type of social cognition, either
within the patient group or across the entire sample. These findings highlight the importance of cognitive reserve
and social cognition in understanding and potentially mitigating NS in schizophrenia.
Descripción:
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Editorial:
Elsevier
EN:
Schizophrenia Research: Cognition, 2025, 42: 100379.
Financiadores:
Citación:
Lema Spinelli, S, Rodríguez-Testal, J, Cabana Fajardo, Á [y otros autores]. "Relationship between cognitive reserve (education), social cognition and negative symptoms". Schizophrenia Research: Cognition. [en línea] 2025, 42: 100379. 8 h. DOI: 10.1016/j.scog.2025.100379
Citación:
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ISBN:
e-ISBN:
ISSN:
2215-0013
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Licencia:
Licencia Creative Commons Atribución - No Comercial - Sin Derivadas (CC - By-NC-ND 4.0)
Colecciones:
| Ficheros | Descripción | Tamaño | Formato | ||
|---|---|---|---|---|---|
| 10.1016.j.scog.2025.100379.pdf | — | 640.63 KB | Adobe PDF |