Título:
Beyond cannabinoids: application of NMR-based metabolomics for the assessment of Cannabis sativa L. crop health
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Autor:
Fernández, Santiago
Castro, Rossina
López-Radcenco, Andrés
Rodriguez, Paula
Carrera, Inés
García-Carnelli, Carlos
Moyna, Guillermo
Castro, Rossina
López-Radcenco, Andrés
Rodriguez, Paula
Carrera, Inés
García-Carnelli, Carlos
Moyna, Guillermo
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Tipo de documento:
Artículo
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Palabras clave:
CANNABIS SATIVA
CANNABINOIDES
METABOLOMICA
OIDIO
HONGOS
QUIMIOVAR
CANNABINOIDES
METABOLOMICA
OIDIO
HONGOS
QUIMIOVAR
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Año de publicación:
2023
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Resumen:
While Cannabis sativa L. varieties have been traditionally characterized by their major cannabinoid profile, it is now well established that other plant metabolites can also have physiological effects, including minor cannabinoids, terpenes, and flavonoids. Given the multiple applications of cannabis in the medical field, it is therefore critical to characterize it according to its chemical composition (i.e., its metabolome) and not only its botanical traits. With this in mind, the cannabinoid and metabolomic profiles from inflorescences of two C. sativa varieties with either high D9 -tetrahydrocannabinolic acid (THCA) or high cannabidiolic acid (CBDA) contents harvested at different times were studied. According to results from HPLC and NMR-based untargeted metabolomic analyses of organic and aqueous plant material extracts, we show that in addition to expected variations according to cannabinoid profiles, it is possible to distinguish between harvests of the same variety. In particular, it was possible to correlate variations in the metabolome with presence of powdery mildew, leading to the identification of molecular markers associated with this fungal infection in C. sativa.
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Frontiers Media
EN:
Frontiers in Plant Science v.14, 2023. -- 10 h.
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Citación:
Fernández, S, Castro, R, López-Radcenco, A, [y otros autores]. "Beyond cannabinoids: application of NMR-based metabolomics for the assessment of Cannabis sativa L. crop health". Frontiers in Plant Science. [en línea] 2023, 14: 10 h., doi: 10.3389/fpls.2023.1025932
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Licencia Creative Commons Atribución (CC - By 4.0)
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| Ficheros | Descripción | Tamaño | Formato | ||
|---|---|---|---|---|---|
| AA Fernandez, S. et al Frontiers in Plant Science 2023.pdf | — | 2.7 MB | Adobe PDF |