| Metadato | Etiqueta | Valor | Idioma |
|---|---|---|---|
| dc.contributor.author | Autor | Cabrera Castro, Andrés M. | - |
| dc.contributor.author | Autor | Romero, David | - |
| dc.contributor.author | Autor | Guerrero, José Carlos | - |
| dc.contributor.author | Autor | Clara, Mario | - |
| dc.contributor.author | Autor | Delfraro Vázquez, Adriana Beatriz | - |
| dc.contributor.filiacion | Filiación | Cabrera Castro Andrés M., Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Biología. | - |
| dc.contributor.filiacion | Filiación | Romero David, Universidad de Málaga | - |
| dc.contributor.filiacion | Filiación | Guerrero José Carlos, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Ecología y Ciencias Ambientales. | - |
| dc.contributor.filiacion | Filiación | Clara Mario, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Ecología y Ciencias Ambientales. | - |
| dc.contributor.filiacion | Filiación | Delfraro Vázquez Adriana Beatriz, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Biología. | - |
| dc.coverage.spatial | Cobertura geográfica | URUGUAY | es |
| dc.date.accessioned | Fecha ingreso | 2024-03-01T15:06:09Z | - |
| dc.date.available | Fecha disponible | 2024-03-01T15:06:09Z | - |
| dc.date.issued | Año de publicación | 2023 | - |
| dc.description.abstract | Resumen | Hantaviruses are the causative agents of hantavirus pulmonary syndrome (HPS) in the Americas. In Central and South America, 28 hantavirus lineages were associated with diferent Sigmodontinae rodents. Of these, Lechiguanas hantavirus was initially described as a lineage associated with HPS cases in the central region of Argentina. Initial studies on the rodent hosts and viral lineages performed between 1999 and 2005 showed that HPS cases in Uruguay were distributed mostly in the southern region of the country, and that the Lechiguanas hantavirus (LECV) and the closely related Andes Central Plata hantaviruses were the viral lineages most frequently associated with HPS cases, both carried by the yellow pygmy rice rat (Oligoryzomys favescens). Although these rodents are present all across the Uruguayan territory, determining the extent of the risk areas for hantavirus transmission based on the distribution of the infected rodents may be a useful tool for disease control and prevention. Distribution models are positioned as an efective instrument in the prediction of diseases afecting human health. Assessment of the potential distribution of rodent reservoir hosts and analysis of the infuence of environmental factors on hantavirus transmission can help to understand the spatial patterns of disease transmission risk. In the present study, virological studies and species distribution models were integrated to understand the hantavirus infection risk pattern in Uruguay. Virological analyses confrmed that in Uruguay, the primary hantavirus reservoir host for both viral lineages is the yellow pygmy rice rat. Additionally, we report an Azara’s grass mouse (Akodon azarae) infected with the Andes Central Plata viral lineage. Based on the seropositive and nonseropositive yellow pygmy rice rats tested, the distribution models emphasized that favorable environmental conditions for the infected rodents are mainly related to the availability of human-disturbed rural environments with high humidity. We conclude that the innovative application of the methodologies reported herein allowed for the assessment of the current risk territory for HPS in Uruguay. | es |
| dc.description.sponsorship | Financiadores | ANII: FMV_3_2011_1_6544 | es |
| dc.format.extent | Extensión | 15 h. | es |
| dc.format.mimetype | Formato | application/pdf | es |
| dc.identifier.citation | Citación | Cabrera Castro, A, Romero, D, Guerrero, J [y otros autores]. "Deciphering the Hantavirus host range combining virology and species distribution models with an emphasis on the Yellow Pygmy Rice Rat (Oligoryzomys flavescens)". Transboundary and Emerging Diseases. [en línea] 2023: 2730050. 15 h. DOI: 10.1155/2023/2730050. | es |
| dc.identifier.doi | DOI | 10.1155/2023/2730050 | - |
| dc.identifier.issn | ISSN | 1865-1682 | - |
| dc.identifier.uri | URI | https://hdl.handle.net/20.500.12008/42848 | - |
| dc.language.iso | Idioma | en | es |
| dc.publisher | Editorial | Wiley | es |
| dc.relation.ispartof | EN | Transboundary and Emerging Diseases, 2023: 2730050. | es |
| dc.rights | Derechos | Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014) | es |
| dc.rights.licence | Licencia | Licencia Creative Commons Atribución (CC - By 4.0) | es |
| dc.subject | Palabras clave | Hantaviruses | es |
| dc.subject | Palabras clave | Oligoryzomys flavescens | es |
| dc.subject | Palabras clave | Distribution models | es |
| dc.subject | Palabras clave | Virological analyses | es |
| dc.subject | Palabras clave | Disease transmission risk | es |
| dc.title | Título | Deciphering the Hantavirus host range combining virology and species distribution models with an emphasis on the Yellow Pygmy Rice Rat (Oligoryzomys flavescens) | es |
| dc.type | Tipo de documento | Artículo | es |
Colecciones:
| Ficheros | Descripción | Tamaño | Formato | ||
|---|---|---|---|---|---|
| 10.1155.2023.2730050.pdf | — | 1.66 MB | Adobe PDF |