| Metadato | Etiqueta | Valor | Idioma |
|---|---|---|---|
| dc.contributor.author | Autor | Sanguinetti Scheck, Juan Ignacio | - |
| dc.contributor.author | Autor | Brecht, M. | - |
| dc.contributor.filiacion | Filiación | Sanguinetti Scheck Juan Ignacio, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Biología. | - |
| dc.contributor.filiacion | Filiación | Brecht M. | - |
| dc.date.accessioned | Fecha ingreso | 2022-05-26T12:41:49Z | - |
| dc.date.available | Fecha disponible | 2022-05-26T12:41:49Z | - |
| dc.date.issued | Año de publicación | 2020 | - |
| dc.description.abstract | Resumen | The home is a unique location in the life of humans and animals. In rats, home presents itself as a multicompartmental space that involves integrating navigation through subspaces. Here we embedded the laboratory rat’s home cage in the arena, while recording neurons in the animal’s parasubiculum and medial entorhinal cortex, two brain areas encoding the animal’s location and head direction. We found that head direction signals were unaffected by home cage presence or translocation. Head direction cells remain globally stable and have similar properties inside and outside the embedded home. We did not observe egocentric bearing encoding of the home cage. However, grid cells were distorted in the presence of the home cage. While they did not globally remap, single firing fields were translocated toward the home. These effects appeared to be geometrical in nature rather than a home-specific distortion and were not dependent on explicit behavioral use of the home cage during a hoarding task. Our work suggests that medial entorhinal cortex and parasubiculum do not remap after embedding the home, but local changes in grid cell activity overrepresent the embedded space location and might contribute to navigation in complex environments. | es |
| dc.format.extent | Extensión | 15 h. | es |
| dc.format.mimetype | Formato | application/pdf | es |
| dc.identifier.citation | Citación | Sanguinetti Scheck, J y Brecht, M. "Home, head direction stability, and grid cell distortion". Journal of Neurophysiology. [en línea] 2020, 123(4): 1392–1406. 15 h. DOI: 10.1152/jn.00518.2019 | es |
| dc.identifier.doi | DOI | 10.1152/jn.00518.2019 | - |
| dc.identifier.issn | ISSN | 1522-1598 | - |
| dc.identifier.uri | URI | https://hdl.handle.net/20.500.12008/31675 | - |
| dc.language.iso | Idioma | en | es |
| dc.publisher | Editorial | American Physiological Society | es |
| dc.relation.ispartof | EN | Journal of Neurophysiology, 2020, 123(4): 1392–1406 | es |
| dc.rights | Derechos | Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014) | es |
| dc.rights.licence | Licencia | Licencia Creative Commons Atribución (CC - By 4.0) | es |
| dc.subject | Palabras clave | Grid cell | es |
| dc.subject | Palabras clave | Head direction | es |
| dc.subject | Palabras clave | Home | es |
| dc.subject | Palabras clave | Homing | es |
| dc.subject | Palabras clave | Navigation | es |
| dc.title | Título | Home, head direction stability, and grid cell distortion | es |
| dc.type | Tipo de documento | Artículo | es |
Colecciones:
| Ficheros | Descripción | Tamaño | Formato | ||
|---|---|---|---|---|---|
| 10.1152jn.00518.2019.pdf | — | 4.35 MB | Adobe PDF |