| Metadato | Etiqueta | Valor | Idioma |
|---|---|---|---|
| dc.contributor.author | Autor | Castells Bauer, Matías | - |
| dc.contributor.author | Autor | Benítez-Galeano, María José | - |
| dc.contributor.author | Autor | Marandino, Ana | - |
| dc.contributor.author | Autor | Caffarena, Rubén Darío | - |
| dc.contributor.author | Autor | Casaux, María Laura | - |
| dc.contributor.author | Autor | Pérez Crossa, Ruben Gustavo | - |
| dc.contributor.author | Autor | Giannitti, Federico | - |
| dc.contributor.author | Autor | Colina, Rodney | - |
| dc.contributor.filiacion | Filiación | Castells Bauer Matías, Universidad de la República (Uruguay). CENUR. | - |
| dc.contributor.filiacion | Filiación | Benítez-Galeano María José, Universidad de la República (Uruguay). CENUR. | - |
| dc.contributor.filiacion | Filiación | Marandino Ana, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Biología. | - |
| dc.contributor.filiacion | Filiación | Caffarena Rubén Darío, Universidad de la República (Uruguay). Facultad de Veterinaria. | - |
| dc.contributor.filiacion | Filiación | Casaux María Laura, INIA | - |
| dc.contributor.filiacion | Filiación | Pérez Crossa Ruben Gustavo, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Biología. | - |
| dc.contributor.filiacion | Filiación | Giannitti Federico, INIA | - |
| dc.contributor.filiacion | Filiación | Colina Rodney, Universidad de la República (Uruguay). CENUR. | - |
| dc.coverage.spatial | Cobertura geográfica | Uruguay | es |
| dc.date.accessioned | Fecha ingreso | 2025-05-28T17:59:44Z | - |
| dc.date.available | Fecha disponible | 2025-05-28T17:59:44Z | - |
| dc.date.issued | Año de publicación | 2024 | - |
| dc.description.abstract | Resumen | Bovine torovirus (BToV) is an enteric pathogen that may cause diarrhea in calves and adult cattle, which could result in economic losses due to weight loss and decreased milk production. This study aimed to report the presence, the genetic characterization and the evolution of BToV in calves in Uruguay. BToV was detected in 7.9% (22/278) of fecal samples, being identified in dairy (9.2%, 22/239) but not beef (0.0%, 0/39) calves. BToV was detected in both diarrheic (14%, 6/43) and non-diarrheic (13.2%, 5/38) dairy calves. In addition, BToV was detected in the intestinal contents of 14.9% (7/47) of naturally deceased dairy calves. A complete genome (28,446 nucleotides) was obtained, which was the second outside Asia and the first in Latin America. In addition, partial S gene sequences were obtained to perform evolutionary analyses. Nucleotide and amino acid substitutions within and between outbreaks/farms were observed, alerting the continuous evolution of the virus. Through Bayesian analysis using BEAST, a recent origin (mid-60s) of BToV, possibly in Asia, was estimated, with two introductions into Uruguay from Asia and Europe in 2004 and 2013, respectively. The estimated evolutionary rate was 1.80 × 10−3 substitutions/site/year. Our findings emphasize the importance of continued surveillance and genetic characterization for the effective management and understanding of BToV’s global epidemiology and evolution. | es |
| dc.description.sponsorship | Financiadores | ANII: FCE_3_2022_1_172734 | es |
| dc.description.sponsorship | Financiadores | ANII: FMV_1_2014_104922 | es |
| dc.format.extent | Extensión | 10 h | es |
| dc.format.mimetype | Formato | application/pdf | es |
| dc.identifier.citation | Citación | Castells Bauer, M, Benítez Galeano, M, Marandino, A [y otros autores]. "Detection and genetic characterization of Bovine Torovirus in Uruguay". Viruses. [en línea] 2024, 16: 835. 10 h. DOI: 10.3390/v16060835 | es |
| dc.identifier.doi | DOI | 10.3390/v16060835 | - |
| dc.identifier.issn | ISSN | 1999-4915 | - |
| dc.identifier.uri | URI | https://hdl.handle.net/20.500.12008/50162 | - |
| dc.language.iso | Idioma | en | es |
| dc.publisher | Editorial | MDPI | es |
| dc.relation.ispartof | EN | Viruses, 2024, 16: 835. | es |
| dc.rights | Derechos | Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014) | es |
| dc.rights.licence | Licencia | Licencia Creative Commons Atribución (CC - By 4.0) | es |
| dc.subject | Palabras clave | Bovine torovirus | es |
| dc.subject | Palabras clave | Cattle | es |
| dc.subject | Palabras clave | Complete genome | es |
| dc.subject | Palabras clave | Genetic diversity | es |
| dc.subject | Palabras clave | Evolution | es |
| dc.title | Título | Detection and genetic characterization of Bovine Torovirus in Uruguay | es |
| dc.type | Tipo de documento | Artículo | es |
Colecciones:
| Ficheros | Descripción | Tamaño | Formato | ||
|---|---|---|---|---|---|
| 10.3390-v16060835.pdf | — | 1.37 MB | Adobe PDF |