Título:
Proinflammatory dietary pattern and depression risk in older adults: Prospective analyses from the Seniors-ENRICA studies
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Autor:
Bizzozero-Peroni, Bruno
Ortola, Rosario
Martínez-Vizcaíno, Vicente
Rodríguez-Artalejo, Fernando
Fernandez-Rodríguez, Ruben
Banegas, Jose R.
Lopez-Garcia, Esther
Eumann Mesas, Arthur
Ortola, Rosario
Martínez-Vizcaíno, Vicente
Rodríguez-Artalejo, Fernando
Fernandez-Rodríguez, Ruben
Banegas, Jose R.
Lopez-Garcia, Esther
Eumann Mesas, Arthur
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Tipo de documento:
Artículo
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Palabras clave:
Dietary inflammatory index
Health behaviour Mental health
Older age
Health behaviour Mental health
Older age
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Año de publicación:
2022
Contenido:
Resumen:
Background & aims: Only a few studies have assessed the association between a proinflammatory diet
and the risk of depression in older adults, and they have rendered weak results. The present study
analysed the association between the Dietary Inflammatory Index (DII) and incident self-reported
diagnosis or symptoms of depression in two cohorts of community-dwelling older adults in Spain.
Methods: We used data from the Seniors-ENRICA-I (SE-I) and Seniors-ENRICA-II (SE-II) cohorts. In both
cohorts, the baseline DII was calculated from habitual food consumption estimated with a validated
computer-based diet history. The incidence of both physician self-reported diagnosis of depression and
mild-to-major depressive symptoms (3 on the 10-item Geriatric Depression Scale) was analysed. Logistic regression models were adjusted for the main potential confounders, such as sociodemographics,
lifestyles, and comorbidities. The results of both cohorts were pooled using a random effects model.
Results: Among the 1627 participants in SE-I (mean age 71.5 ± 5.5 y, 53.1% women) and the 1579 in SE-II
(mean age 71.4 ± 4.2, 46.7% women), 86 (5.3%) and 140 (8.9%) incident cases of depression were identified after a mean 3.2-y and 2.3-y follow-up, respectively. The fully adjusted odds ratio (95% confidence
interval) of incident depression for the highest (the highest proinflammatory diet) versus the lowest
quartile of DII was 2.76 (1.25e6.08, p-for-trend ¼ 0.005) in the SE-I, 1.90 (1.04e3.40, p-for-trend ¼ 0.005)
in the SE-II and 2.07 (1.01e3.13) in the pooled cohorts. The results were consistent across strata defined
by sex, age, physical activity, loneliness/poor social network, and morbidity.
Conclusions: A proinflammatory dietary pattern is associated with depression risk in older adults. Future
research should evaluate whether reducing the inflammatory component of diet leads to reduced
depression symptoms in this population
Descripción:
Becas de Posgrado en el Exterior 2020: código POS_EXT_2020_1_165371
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Editorial:
Elsevier
EN:
Clinical Nutrition, 41 (2022) 2614-2620
Financiadores:
Agencia Nacional de Investigación e Innovación (ANII)
Citación:
Bizzozero-Peroni, B, Ortola, R, Martínez-Vizcaíno, V, y otros. "Proinflammatory dietary pattern and depression risk in older adults: Prospective analyses from the Seniors-ENRICA studies". Clinical Nutrition. [en línea] 41 (2022) 2614-2620 Doi :https://doi.org/10.1016/j.clnu.2022.10.007
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Licencia:
Licencia Creative Commons Atribución - No Comercial - Sin Derivadas (CC - By-NC-ND 4.0)
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|---|---|---|---|---|---|
| Articulo 3_versión-final-publicada.pdf | — | 297.7 KB | Adobe PDF |