| Metadato | Etiqueta | Valor | Idioma |
|---|---|---|---|
| dc.contributor.author | Autor | Pereira Gómez, Marianoel | - |
| dc.contributor.author | Autor | Arce Rama, Rodrigo | - |
| dc.contributor.author | Autor | Ferla, Diego | - |
| dc.contributor.author | Autor | Simón, Diego | - |
| dc.contributor.author | Autor | Salazar González, María Cecilia | - |
| dc.contributor.author | Autor | Perbolianachis Duarte, Paula | - |
| dc.contributor.author | Autor | Costábile Cristech, Alicia | - |
| dc.contributor.author | Autor | Fajardo Rossi, Álvaro | - |
| dc.contributor.author | Autor | Aldunate Caramori, Fabián | - |
| dc.contributor.author | Autor | Nin, Nicolás | - |
| dc.contributor.author | Autor | Hurtado, Francisco Javier | - |
| dc.contributor.author | Autor | Iraola, Gregorio | - |
| dc.contributor.author | Autor | Moreno Karlen, María del Pilar | - |
| dc.contributor.author | Autor | Moratorio, Gonzalo | - |
| dc.contributor.filiacion | Filiación | Pereira Gómez Marianoel, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares. | - |
| dc.contributor.filiacion | Filiación | Arce Rama Rodrigo, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares. | - |
| dc.contributor.filiacion | Filiación | Ferla Diego, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares. | - |
| dc.contributor.filiacion | Filiación | Simón Diego, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares. | - |
| dc.contributor.filiacion | Filiación | Salazar González María Cecilia, Instituto Pasteur (Montevideo) | - |
| dc.contributor.filiacion | Filiación | Perbolianachis Duarte Paula, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares. | - |
| dc.contributor.filiacion | Filiación | Costábile Cristech Alicia, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Biología. | - |
| dc.contributor.filiacion | Filiación | Fajardo Rossi Álvaro, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares. | - |
| dc.contributor.filiacion | Filiación | Aldunate Caramori Fabián, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares. | - |
| dc.contributor.filiacion | Filiación | Nin Nicolás, ASSE | - |
| dc.contributor.filiacion | Filiación | Hurtado Francisco Javier, ASSE | - |
| dc.contributor.filiacion | Filiación | Iraola Gregorio, Instituto Pasteur (Montevideo) | - |
| dc.contributor.filiacion | Filiación | Moreno Karlen María del Pilar, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares. | - |
| dc.contributor.filiacion | Filiación | Moratorio Gonzalo, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares. | - |
| dc.date.accessioned | Fecha ingreso | 2024-02-23T14:43:12Z | - |
| dc.date.available | Fecha disponible | 2024-02-23T14:43:12Z | - |
| dc.date.issued | Año de publicación | 2023 | - |
| dc.description.abstract | Resumen | Understanding transmission routes of SARS-CoV-2 is crucial to establish effective interventions in healthcare institutions. Although the role of surface contamination in SARS-CoV-2 transmission has been controversial, fomites have been proposed as a contributing factor. Longitudinal studies about SARS-CoV-2 surface contamination in hospitals with different infrastructure (presence or absence of negative pressure systems) are needed to improve our understanding of their effectiveness on patient healthcare and to advance our knowledge about the viral spread. We performed a one-year longitudinal study to evaluate surface contamination with SARS-CoV2 RNA in reference hospitals. These hospitals have to admit all COVID-19 patients from public health services that require hospitalization. Surfaces samples were molecular tested for SARSCoV-2 RNA presence considering three factors: the dirtiness by measuring organic material, the circulation of a high transmissibility variant, and the presence or absence of negative pressure systems in hospitalized patients’ rooms. Our results show that: (i) There is no correlation between the amount of organic material dirtiness and SARS-CoV-2 RNA detected on surfaces; (ii) SARS-CoV-2 high transmissible Gamma variant introduction significantly increased surface contamination; (iii) the hospital with negative pressure systems was associated with lower levels of SARS-CoV-2 surface contamination and, iv) most environmental samples recovered from contaminated surfaces were assigned as noninfectious. This study provides data gathered for one year about the surface contamination with SARSCoV-2 RNA sampling hospital settings. Our results suggest that spatial dynamics of SARS-CoV-2 RNA contamination varies according with the type of SARS-CoV-2 genetic variant and the presence of negative pressure systems. In addition, we showed that there is no correlation between the amount of organic material dirtiness and the quantity of viral RNA detected in hospital settings. Our findings suggest that SARS CoV-2 RNA surface contamination monitoring might be useful for the understanding of SARS-CoV-2 dissemination with impact on hospital management and public health policies. This is of special relevance for the Latin-American region where ICU rooms with negative pressure are insufficient. | es |
| dc.format.extent | Extensión | 11 h. | es |
| dc.format.mimetype | Formato | application/pdf | es |
| dc.identifier.citation | Citación | Pereira Gómez, M, Arce Rama, R, Ferla, D [y otros autores]. "One-year monitoring SARS-CoV-2 RNA surface contamination in hospitals reveals no correlation with organic material and negative pressure as a limiting factor for contamination". Heliyon. [en línea] 2023, 9(3): e13875. 11 h. DOI: 10.1016/j.heliyon.2023.e13875. | es |
| dc.identifier.doi | DOI | 10.1016/j.heliyon.2023.e13875 | - |
| dc.identifier.issn | ISSN | 2405-8440 | - |
| dc.identifier.uri | URI | https://hdl.handle.net/20.500.12008/42617 | - |
| dc.language.iso | Idioma | en | es |
| dc.publisher | Editorial | Cell Press | es |
| dc.relation.ispartof | EN | Heliyon, 2023, 9(3): e13875 | es |
| dc.rights | Derechos | Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014) | es |
| dc.rights.licence | Licencia | Licencia Creative Commons Atribución - No Comercial - Sin Derivadas (CC - By-NC-ND 4.0) | es |
| dc.subject | Palabras clave | SARS-CoV2 RNA | es |
| dc.subject | Palabras clave | Ct value | es |
| dc.subject | Palabras clave | Fomites | es |
| dc.subject | Palabras clave | Organic material dirtiness | es |
| dc.subject | Palabras clave | ATP measurements | es |
| dc.subject | Palabras clave | Negative pressure system | es |
| dc.subject | Palabras clave | Variant of concern | es |
| dc.title | Título | One-year monitoring SARS-CoV-2 RNA surface contamination in hospitals reveals no correlation with organic material and negative pressure as a limiting factor for contamination | es |
| dc.type | Tipo de documento | Artículo | es |
Colecciones:
| Ficheros | Descripción | Tamaño | Formato | ||
|---|---|---|---|---|---|
| 10.1016j.heliyon.2023.e13875.pdf | — | 2.51 MB | Adobe PDF |