Por favor, use este identificador para citar o enlazar este ítem: https://hdl.handle.net/20.500.12008/55698
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dc.contributor.author Autor Pereda, Jimena-
dc.contributor.author Autor Bove, Isabel-
dc.contributor.author Autor Piñeyro, María M.-
dc.contributor.filiacion Filiación Pereda Jimena, Universidad de la República (Uruguay). Facultad de Medicina. Hospital de Clínicas. Clínica de Endocrinología y Metabolismo-
dc.contributor.filiacion Filiación Bove Isabel, Universidad Católica del Uruguay (Uruguay). Departamento de Ciencias Cognitivas y de la Salud-
dc.contributor.filiacion Filiación Piñeyro María M., Universidad de la República (Uruguay). Facultad de Medicina. Hospital de Clínicas. Clínica de Endocrinología y Metabolismo-
dc.coverage.spatial Cobertura geográfica URUGUAYes
dc.coverage.temporal Cobertura temporal 2012es
dc.date.accessioned Fecha ingreso 2026-06-25T13:56:20Z-
dc.date.available Fecha disponible 2026-06-25T13:56:20Z-
dc.date.issued Año de publicación 2020-
dc.description.abstract Resumen Objective To evaluate the risk of macrosomia in newborns from women with gestational diabetes, pregestational diabetes, overweight, and obesity in Uruguay in 2012, as well as its association with prolonged pregnancy, maternal age, multiparity, and excessive gestational weight gain (EGWG). Methods We performed a cross-sectional study of 42,663 pregnant women. The risk of macrosomia was studied using logistic regression. Results Mean maternal age was 26.7 ± 6.8 years. Pregestational overweight and obesity was present in 20.9% and 10.7% of women, respectively. There were 28.1% and 19.8% of women overweight and obese at the end of the pregnancy, respectively. Furthermore, 0.5% had pregestational diabetes and 8.5% were multiparous. Twenty two percent developed gestational diabetes and 44.9% had EGWG. The prevalence of macrosomia was 7.9%, significantly more prevalent in males (10.0% vs. 5.5%, p<0.005). Univariate analysis showed that obesity and overweight pre-pregnancy, obesity and overweight at the end of pregnancy, EGWG, pregestational diabetes, gestational diabetes, multiparity, prolonged pregnancy, and male newborn were strongly associated with macrosomia (p<0.0001). Maternal age >35 years did not increase the risk of macrosomia. After multiple logistic regression macrosomia was more likely in pre-gestational obese women (OR 1.24; CI 1.07–1.44), overweight women at the end of pregnancy (OR 1.66; CI 1.46–1.87), obese women at the end of pregnancy (OR 2.21; CI 1.90–2.58), women with EGWG (OR 1.78; CI 1.59–1.98), pregestational diabetes (OR 1.75; CI 1.15–2.69), gestational diabetes (OR 1.39; CI 1.25–1.53), prolonged pregnancy (OR 2.67; CI 2.28–3.12), multiparity (OR 1.24; CI 1.04–1.48), and male newborn (OR 1.89; CI 1.72–2.08). Conclusion Maternal overweight, obesity, EGWG, and gestational diabetes are prevalent in Uruguay, increasing the risk of macrosomia. Efforts to implement strategies to decrease the prevalence of overweight and obesity among women of reproductive age are essential to improve maternal and neonatal outcomes.es
dc.format.extent Extensión 9 p.es
dc.format.mimetype Formato application/pdfes
dc.identifier.citation Citación Pereda J, Bove I y Piñeyro M. Excessive Maternal Weight and Diabetes Are Risk Factors for Macrosomia: A Cross-Sectional Study of 42,663 Pregnancies in Uruguay. Frontiers in Endocrinology [en línea]. 2020;11. 9 p.es
dc.identifier.doi DOI 10.3389/fendo.2020.588443-
dc.identifier.eissn e-ISSN 1664-2392-
dc.identifier.uri URI https://hdl.handle.net/20.500.12008/55698-
dc.language.iso Idioma enes
dc.publisher Editorial Frontiers Research Foundationes
dc.relation.ispartof EN Frontiers in Endocrinology. 2020;11es
dc.rights Derechos Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014)es
dc.rights.licence Licencia Licencia Creative Commons Atribución (CC - By 4.0)es
dc.subject Palabras clave Overweightes
dc.subject Palabras clave Obesityes
dc.subject Palabras clave Pregnancyes
dc.subject Palabras clave Gestational diabeteses
dc.subject Palabras clave Pregestational diabeteses
dc.subject Palabras clave Macrosomiaes
dc.subject.other Descriptores EMBARAZOes
dc.subject.other Descriptores OBESIDADes
dc.subject.other Descriptores SOBREPESOes
dc.subject.other Descriptores DIABETES GESTACIONALes
dc.subject.other Descriptores MACROSOMÍA FETALes
dc.title Título Excessive Maternal Weight and Diabetes Are Risk Factors for Macrosomia: A Cross-Sectional Study of 42,663 Pregnancies in Uruguayes
dc.type Tipo de documento Artículoes
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