Por favor, use este identificador para citar o enlazar este ítem: https://hdl.handle.net/20.500.12008/51795

Título:

The frequency of risk factors for cleft lip and palate in Mexico: a systematic review.

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Autor:

López-Verdín, Sandra
Solorzano-López, Judith A.
Bologna-Molina, Ronell
Molina-Frechero, Nelly
Tremillo-Maldonado, Omar
Toral-Rizo, Víctor Hugo
González González, Rogelio

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Artículo

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Palabras clave:

Cleft lip and palate
Risk factors
Mexican population
Toxic substances

Descriptores:

LABIO LEPORINO
FACTORES DE RIESGO
SUSTANCIAS TÓXICAS

Año de publicación:

2024

Contenido:

Resumen:

Background: Cleft lip and palate is an anomaly that affects both women and men. It is considered to be among the most frequent congenital abnormalities and is related to modifications in chromosomal DNA and multiple genetic alterations. This anomaly can also be associated with various environmental factors, such as tobacco and alcohol consumption, medication use, and exposure to different environmental and industrial toxic substances. The objective of this study was to document the frequency of risk factors related to cleft lip and palate through a systematic review of Mexican studies. Methods: In this systematic review, a bibliographic search was conducted following PRISMA guidelines in the databases Scielo, ScienceDirect, PubMed, and EBSCO. Keywords related to cleft lip and palate, epidemiology, and risk factors were used. In all, 3 independent reviewers (J.A.S.L., S.L.V., and N.M.F.) selected and evaluated a total of 17 articles included in this analysis, achieving a coefficient of κ = 0.84. Results: The analysis revealed that the highest frequency of conducted studies was in the State of Mexico. The most common risk factors identified were environmental, pharmacological, consumption habits, and gynecological factors. Conclusions: Identifying the main risk factors for cleft lip and palate in the Mexican population will enable the implementation of preventive measures aimed at reducing exposure to these factors. Additionally, early intervention can improve the quality of life for individuals affected by this condition.

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MDPI

EN:

Diagnostics, 2024, 14(16): 1753.

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Citación:

López-Verdín, S, Solorzano-López, J, Bologna-Molina, R, [y otros autores] . "The frequency of risk factors for cleft lip and palate in Mexico: a systematic review". Diagnostics. [en línea] 2024, 14(16): 1753. 12 h.

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Licencia Creative Commons Atribución (CC - By 4.0)
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